Safety Warning
DIY auto repair can cause serious injury, fire, or vehicle damage. These guides are for informational purposes only. Always follow OEM torque specs, wear PPE, and consult a certified mechanic if you are unsure. You are solely responsible for your safety.
2021 Lexus LS 500 Base, AWDFACTORY OEM SERVICE PROCEDURE
Engine Control System - Diagnostic Codes (07 Of 14)
- SFI System
- DTC P0300-00: Random/Multiple Cylinder Misfire Detected; DTC P0300-27: Random/Multiple Cylinder Misfire Detected (Emission) Signal Rate of Change Above Threshold; DTC P0300-85: Random / Multiple Cylinder Misfire Detected (Over Temperature) Signal Above Allowable Range; DTC P0301-00: Cylinder 1 Misfire Detected; DTC P0302-00: Cylinder 2 Misfire Detected; DTC P0303-00: Cylinder 3 Misfire Detected; DTC P0304-00: Cylinder 4 Misfire Detected; DTC P0305-00: Cylinder 5 Misfire Detected; DTC P0306-00: Cylinder 6 Misfire Detected [12/2017 - 10/2020]
- DTC P0300-00: Random/Multiple Cylinder Misfire Detected; DTC P0300-27: Random/Multiple Cylinder Misfire Detected (Emission) Signal Rate of Change Above Threshold; DTC P0300-85: Random / Multiple Cylinder Misfire Detected (Over Temperature) Signal Above Allowable Range; DTC P0301-00: Cylinder 1 Misfire Detected; DTC P0302-00: Cylinder 2 Misfire Detected; DTC P0303-00: Cylinder 3 Misfire Detected; DTC P0304-00: Cylinder 4 Misfire Detected; DTC P0305-00: Cylinder 5 Misfire Detected; DTC P0306-00: Cylinder 6 Misfire Detected [10/2020 - 10/2023]
- DTC P0300-00: Random/Multiple Cylinder Misfire Detected; DTC P0300-27: Random/Multiple Cylinder Misfire Detected (Emission) Signal Rate of Change Above Threshold; DTC P0300-85: Random / Multiple Cylinder Misfire Detected (Over Temperature) Signal Above Allowable Range; DTC P0301-00: Cylinder 1 Misfire Detected; DTC P0302-00: Cylinder 2 Misfire Detected; DTC P0303-00: Cylinder 3 Misfire Detected; DTC P0304-00: Cylinder 4 Misfire Detected; DTC P0305-00: Cylinder 5 Misfire Detected; DTC P0306-00: Cylinder 6 Misfire Detected [10/2023 - ]
- DTC P0325-11: Knock Sensor 1 Bank 1 or Single Sensor Circuit Short to Ground; DTC P0330-11: Knock Sensor 2 Bank 2 Circuit Short to Ground [12/2017 - ]
- DTC P0325-15: Knock Sensor 1 Bank 1 or Single Sensor Circuit Short to Battery or Open; DTC P0330-15: Knock Sensor 2 Bank 2 Circuit Short to Battery or Open [12/2017 - ]
- DTC P0335-00: Crankshaft Position Sensor "A" No Signal (sub) [12/2017 - 10/2020]
- DTC P0335-11: Crankshaft Position Sensor "A" Circuit Short to Ground; DTC P0335-15: Crankshaft Position Sensor "A" Circuit Short to Battery or Open [12/2017 - ]
- DTC P0335-1F: Crankshaft Position Sensor "A" Circuit Intermittent; DTC P0335-2A: Crankshaft Position Sensor "A" Signal Stuck in Range; DTC P0335-31: Crankshaft Position Sensor "A" No Signal [12/2017 - ]
- DTC P0340-00: Camshaft Position Sensor "A" Bank 1 or Single Sensor No Signal (sub); DTC P0345-00: Camshaft Position Sensor "A" Bank 2 No Signal (sub) [12/2017 - 10/2020]
- DTC P0340-11: Camshaft Position Sensor "A" Bank 1 or Single Sensor Circuit Short to Ground; DTC P0340-15: Camshaft Position Sensor "A" Bank 1 or Single Sensor Circuit Short to Battery or Open; DTC P0345-11: Camshaft Position Sensor "A" Bank 2 Circuit Short to Ground; DTC P0345-15: Camshaft Position Sensor "A" Bank 2 Circuit Short to Battery or Open [12/2017 - ]
- DTC P0340-31: Camshaft Position Sensor "A" Bank 1 or Single Sensor No Signal; DTC P0345-31: Camshaft Position Sensor "A" Bank 2 No Signal [12/2017 - ]
- DTC P0365-00: Camshaft Position Sensor "B" Bank 1 No Signal (sub); DTC P0390-00: Camshaft Position Sensor "B" Bank 2 No Signal (sub) [12/2017 - 10/2020]
- DTC P0365-11: Camshaft Position Sensor "B" Bank 1 Circuit Short to Ground; DTC P0365-15: Camshaft Position Sensor "B" Bank 1 Circuit Short to Battery or Open; DTC P0390-11: Camshaft Position Sensor "B" Bank 2 Circuit Short to Ground; DTC P0390-15: Camshaft Position Sensor "B" Bank 2 Circuit Short to Battery or Open [12/2017 - ]
- DTC P0365-2A: Camshaft Position Sensor "B" Bank 1 Signal Stuck in Range; DTC P0365-31: Camshaft Position Sensor "B" Bank 1 No Signal; DTC P0390-31: Camshaft Position Sensor "B" Bank 2 No Signal [12/2017 - ]
- DTC P0420-00: Catalyst System Efficiency Below Threshold Bank 1; DTC P0430-00: Catalyst System Efficiency Below Threshold Bank 2 [12/2017 - 10/2020]
- DTC P0420-00: Catalyst System Efficiency Below Threshold Bank 1; DTC P0430-00: Catalyst System Efficiency Below Threshold Bank 2 [10/2020 - 10/2022]
- DTC P0420-00: Catalyst System Efficiency Below Threshold Bank 1; DTC P0430-00: Catalyst System Efficiency Below Threshold Bank 2 [10/2022 - 10/2023]
Factory Service Tools
Use the Manual With the Right Hardware
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When to See a Mechanic
Stop DIY work and contact a certified mechanic immediately if any of the following apply:
- β’ You smell fuel, burning insulation, or see smoke.
- β’ Brakes feel soft, pull hard to one side, or make grinding noises.
- β’ The engine overheats, stalls repeatedly, or misfires under load.
- β’ You are missing required tools, torque specs, or safe lifting equipment.
- β’ You are not confident in the next step or safety outcome.
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